Document Detail

Testicular mixed germ-cell tumor metastatic to the choroid.
MedLine Citation:
PMID:  25389834     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: To describe the fundus findings, ultrasonography, and fluorescein angiography of a testicular mixed germ-cell tumor metastatic to the choroid and to report prompt resolution of the choroidal lesion with systemic chemotherapy.
METHODS: Observational case report. A 21-year-old man presented with a 10-cm testicular tumor. Ophthalmic examination revealed a large, dome-shaped choroidal lesion in the left eye, filling the entire superotemporal quadrant and extending into the macula. Ultrasonography showed a 10.3 mm in thickness hyperechoic mass. The patient was started on vinblastine, mesna, ifosfamide, and cisplatin.
RESULTS: On ophthalmic examination 6 weeks after initiation of chemotherapy, the choroidal lesion had completely resolved, leaving only pigmentary changes. Final ophthalmology follow-up 8 months after presentation demonstrated no recurrence of choroidal metastases.
CONCLUSION: Testicular germ-cell tumors have now been well described to metastasize to the choroid. These choroidal metastases can show a prompt, favorable response to chemotherapy.
Mohammed K ElMallah; Allen M Chernoff; Norman P Blair
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Retinal cases & brief reports     Volume:  2     ISSN:  1935-1089     ISO Abbreviation:  Retin Cases Brief Rep     Publication Date:  2008  
Date Detail:
Created Date:  2014-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101298744     Medline TA:  Retin Cases Brief Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  172-4     Citation Subset:  -    
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