Document Detail


Testicular mixed germ cell tumor with polyembryoma component in brothers.
MedLine Citation:
PMID:  15803215     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a 17-year-old male with a testicular tumor and high serum levels of alpha-fetoprotein. The patient was treated with surgery followed by combination chemotherapy with bleomycin, etoposide, and cisplatin. Histologic examination showed features of a mixed germ cell tumor composed of mature teratoma, immature teratoma, embryonal carcinoma, yolk sac tumor, and polyembryoma. He is currently well, and his serum levels of alpha-fetoprotein have been normal more than 5 months after treatment. His brother, aged 17 years at the time, had a similar tumor removed from the right testicle 5 years previously.
Authors:
Sevgi Bakaris; Sefa Resim; Nurdan Tunali
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2004-12-06
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  8     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2005-04-01     Completed Date:  2005-06-28     Revised Date:  2006-05-08    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  92-7     Citation Subset:  IM    
Affiliation:
Department of Pathology, Kahramanmaras Sutcuimam University Medical School, 46050 Kahramanmaras, Turkey. sevgiba@superonline.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Antineoplastic Combined Chemotherapy Protocols / administration & dosage,  therapeutic use
Bleomycin / administration & dosage
Cisplatin / administration & dosage
Combined Modality Therapy
Etoposide / administration & dosage
Humans
Immunohistochemistry
Male
Neoplasms, Germ Cell and Embryonal / metabolism,  pathology*,  therapy
Siblings*
Testicular Neoplasms / metabolism,  pathology*,  therapy
Tumor Markers, Biological / metabolism
alpha-Fetoproteins / metabolism
Chemical
Reg. No./Substance:
0/BEP protocol; 0/Tumor Markers, Biological; 0/alpha-Fetoproteins; 11056-06-7/Bleomycin; 15663-27-1/Cisplatin; 33419-42-0/Etoposide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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