Document Detail

Testicular microlithiasis heralding mixed germ cell tumor of the testis in a boy.
MedLine Citation:
PMID:  16553039     Owner:  NLM     Status:  MEDLINE    
The clinical implications of the association between testicular microlithiasis (TM) and germ cell tumor (GCT) of the testis are still debated since the natural history of incidentally discovered TM has not been defined. Therefore, it is questionable whether TM can be considered as a precursor of malignancy. We are reporting the case of a 9-yr-old boy with a mixed GCT who had presented 3 yr earlier with TM and hydrocele. This evolution suggests that testicular GCT may develop some years later in a boy with pre-existing and incidentally discovered TM. Our case history and other reports of the literature might suggest a strong association between both conditions, thus vindicating the view that individuals with TM should have clinical and ultrasound follow-up. Longitudinal evaluation may be particularly indicated in the patients with additional testicular dysgenetic features, apart from TM.
T Arrigo; M F Messina; M Valenzise; M Rosano; R Alaggio; G Cecchetto; G Zirilli; F De Luca
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  29     ISSN:  0391-4097     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-03-23     Completed Date:  2006-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  82-5     Citation Subset:  IM    
Department of Pediatrics, University of Messina, Messina, Italy.
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MeSH Terms
Lithiasis / diagnosis*,  pathology,  ultrasonography
Neoplasms, Germ Cell and Embryonal / diagnosis*,  pathology,  ultrasonography
Testicular Diseases / diagnosis*,  pathology,  ultrasonography
Testicular Neoplasms / diagnosis,  pathology,  ultrasonography

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