| Testicular changes in newborn rats exposed to phototherapy. | |
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MedLine Citation:
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PMID: 10347276 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study we investigated the long-term effects of 72-h continuous phototherapy on the reproductive system of newborn rats. The animals' weight, fertilization rates, and number of newborn and histopathological changes in the gonads in a normal group not exposed to phototherapy and in the test animals were compared. At the age of 24 weeks there were no significant differences between the two groups, apart from the histology of the testicles of the male rats who were exposed to the phototherapy. The study group showed a significantly reduced diameter of the seminiferous tubules when compared to the controls (P < 0.001). It can be postulated that phototherapy may cause histological degenerative changes in the structure of the rat's testes, even though there were no changes in fertilization rates. Further studies are necessary to reveal the effects of phototherapy on humans and to determine the effects, if any, on fertility. |
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Authors:
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H Koç; H Altunhan; A Dilsiz; A Kaymakçi; S Duman; B Oran; I Erkul |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society Volume: 2 ISSN: 1093-5266 ISO Abbreviation: Pediatr. Dev. Pathol. Publication Date: 1999 Jul-Aug |
Date Detail:
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Created Date: 1999-07-16 Completed Date: 1999-07-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9809673 Medline TA: Pediatr Dev Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 333-6 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Faculty of Medicine, University of Selçuk, 42080 Konya, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn Body Temperature Body Weight / radiation effects Female Fertility / radiation effects Litter Size Male Ovary / pathology, radiation effects Phototherapy / adverse effects* Pregnancy Radiation Injuries, Experimental / etiology*, pathology Rats Rats, Wistar Seminiferous Tubules / pathology, radiation effects Testicular Diseases / etiology*, pathology Testis / pathology, radiation effects* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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