| Testicular blood flow following spinal cord injury in the Sprague Dawley rat. | |
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MedLine Citation:
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PMID: 8819026 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The causes of poor semen quality following spinal cord injury (SCI) are unknown. One possible mechanism is decreased testicular blood flow. Chronic testicular ischemia in non-SCI animals has been shown to have significant adverse impact on spermatogenesis. This study was designed to evaluate testicular blood flow following SCI in the Sprague Dawley rat. Testicular blood flows were determined in 11 rats with SCI at thoracic level nine (T9) and six sham control rats three days prior and three days and 14 days after SCI. Testicular blood flow velocity was measured with a Doppler flow probe. Blood flows were compared between groups using T-tests. There were no significant changes in blood flow in the sham operated rats three or 14 days after surgery. However, three days after SCI, blood flow had decreased in the SCI rats to 78 +/- 5 percent of the pre-SCI flow (t = -4.65 with 10 df, p < 0.001). At 14 days after SCI, blood flow was still decreased to 77 +/- 8 percent, (t = -3.40 with 3 df, p < 0.05). This study established that following SCI, testicular blood flow decreases in the Sprague Dawley rat. |
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Authors:
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T A Linsenmeyer; Q Chang; J Ottenweller; R Anesetti; L Pogach; H H Huang |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The journal of spinal cord medicine Volume: 19 ISSN: 1079-0268 ISO Abbreviation: J Spinal Cord Med Publication Date: 1996 Jul |
Date Detail:
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Created Date: 1996-12-27 Completed Date: 1996-12-27 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9504452 Medline TA: J Spinal Cord Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 183-5 Citation Subset: IM |
Affiliation:
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Kessler Institute for Rehabilitation, Department of Urology, West Orange, NJ 07052, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Flow Velocity / physiology Fourier Analysis Ischemia / physiopathology Male Rats Rats, Sprague-Dawley Rheology / instrumentation Signal Processing, Computer-Assisted / instrumentation Spermatogenesis / physiology Spinal Cord Injuries / physiopathology* Testis / blood supply* |
| Grant Support | |
ID/Acronym/Agency:
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HD 30140/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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