Document Detail

Test-retest reliability of pulse wave velocity in individuals with chronic spinal cord injury.
MedLine Citation:
PMID:  23031177     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Pulse wave velocity (PWV), which reflects arterial stiffness, is an important predictor of future coronary artery disease. The test-retest reliability of PWV has not been investigated in people with spinal cord injury (SCI).
PURPOSE: To report the test-retest (day-to-day) reliability of PWV measurements among people with SCI, and to determine the smallest real difference (SRD) of PWV values.
PARTICIPANTS: Twenty men (n = 19) and a woman (n = 1) with SCI (C4-T10; AIS A-D; ≥ 1-year post-injury; 10 with paraplegia and 10 with tetraplegia; time post-injury: 11.8 ± 8.7 years; age: 43.0 ± 12.6 years).
METHODS: On two occasions within a 2-week period, aortic PWV (between the common carotid and femoral artery), arm PWV (between the brachial and radial artery), and leg PWV (between femoral and posterior tibial artery) were assessed at the same time of day using Doppler flowmeters.
RESULTS: No statistically significant differences were found between days 1 and 2 in aortic PWV (day 1: 941 ± 185 cm/seconds, day 2: 917 ± 160 cm/seconds, P = 0.257), leg PWV (day 1: 1088 ± 141 cm/seconds, day 2: 1122 ± 165 cm/seconds, P = 0.099) and arm PWV (day 1: 1283 ± 185 cm/seconds, day 2: 1358 ± 256 cm/seconds, P = 0.180). The aortic and leg PWVs had high test-retest reliability (intraclass correlation coefficient: ICC = 0.920 and 0.913, respectively; P < 0.001 for both) and arm PWV had moderate test-retest reliability (ICC = 0.598, P = 0.03). SRDs for each PWV were 104 cm/seconds (aortic PWV), 97 cm/seconds (leg PWV) and 143 cm/seconds (arm PWV).
CONCLUSION: The test-retest reliability of PWV assessment is high among patients with chronic SCI. Changes in aortic PWV values above 104 cm/seconds with repeated testing like represent true changes in health status.
Masae Miyatani; Kei Masani; Cameron Moore; Maggie Szeto; Maggie Szato; Paul Oh; Catharine Craven
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  The journal of spinal cord medicine     Volume:  35     ISSN:  1079-0268     ISO Abbreviation:  J Spinal Cord Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-10-03     Completed Date:  2012-12-31     Revised Date:  2013-09-03    
Medline Journal Info:
Nlm Unique ID:  9504452     Medline TA:  J Spinal Cord Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  400-5     Citation Subset:  IM    
Toronto Rehabilitation Institute, Toronto, Ontario, Canada.
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MeSH Terms
Aorta / physiology
Arm / blood supply
Chronic Disease
Coronary Artery Disease / complications*,  diagnosis*,  physiopathology
Leg / blood supply
Middle Aged
Pulse Wave Analysis / methods*,  standards*
Reproducibility of Results
Spinal Cord Injuries / complications*
Vascular Stiffness / physiology
Erratum In:
J Spinal Cord Med. 2012 Nov;35(6):635
Note: Szato, Maggie [corrected to Szeto, Maggie]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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