Document Detail


Test-retest reliability of DSC MRI CBV mapping in healthy volunteers.
MedLine Citation:
PMID:  11409717     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dynamic susceptibility contrast magnetic resonance imaging (DSC MRI) can be used to generate high resolution maps of cerebral blood volume (CBV). To determine the test-retest reliability, CBV was measured in eight volunteers on two occasions, separated by 4 weeks. The mean ratio (scan 2/scan 1) for 72 cortical regions of interest (ROIs) was 1.03, with a coefficient of variation of 14%. The correlation between the first and second scans was 0.73 (p < 0.0001; 95%). In five hand-drawn ROIs, the mean ratio was 1.08, with a coefficient of variation of 12%. The correlation between scans was 0.84 (p < 0.0001). The data presented here support the hypothesis that DSC MRI CBV mapping has acceptable test-retest reliability.
Authors:
M E Henry; M J Kaufman; N Lange; M E Schmidt; S Purcell; J Cote; D M Perron-Henry; E Stoddard; B M Cohen; P F Renshaw
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neuroreport     Volume:  12     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-06-18     Completed Date:  2001-12-04     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  England    
Other Details:
Languages:  eng     Pagination:  1567-9     Citation Subset:  IM    
Affiliation:
Brain Imaging Center, McLean Hospital and The Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Volume*
Cerebrovascular Circulation*
Female
Humans
Magnetic Resonance Imaging / methods*,  standards*
Male
Reference Values
Reproducibility of Results
Grant Support
ID/Acronym/Agency:
DA-09448/DA/NIDA NIH HHS

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