| Test-bolus injection for optimization of arterial phase imaging during contrast-enhanced hepatic MR imaging. | |
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MedLine Citation:
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PMID: 10992807 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Contrast enhancement during the dynamic MR imaging is important for the detection and characterization of focal liver lesions. The purpose of this study was to determine whether or not a timing examination with a injection of a 1.0-mL bolus of gadopentetate dimeglumine into the antecubital vein followed by rapid dynamic scanning and measurement of signal intensity of the aorta could help to obtain proper arterial-dominant phase images for the characterization of focal hepatic lesions during subsequent multiphase dynamic MR imaging. The imaging delay to acquisition of the first gadolinium-enhanced image for multiphase dynamic MR imaging was set to equal the time to peak aortic enhancement during the test examination. The first contrast-enhanced images of 80 patients with 160 focal liver lesions (hepatocellular carcinoma, n = 79; cavernous hemangioma, n = 51; metastatic tumor, n = 30) were then retrospectively reviewed. Peak aortic enhancement occurred between 10 and 28 seconds (mean, 16.5 seconds +/- 3.1) after starting the infusion of contrast material in 80 patients during the test-examination. Depending on the findings of intrahepatic vascular enhancement on the full-scale dynamic images, hepatic arterial phase (n = 11, 14%) or sinusoid phase (n = 65, 81%) imaging was obtained during the first gadolinium-enhanced acquisition in 76 (95%) of 80 patients. Three different lesions were well characterized and easily distinguished from each other (p < .0001) on the first-phase images depending on their enhancement pattern. In the majority of patients, timing examination with test-bolus injection was helpful in obtaining qualified images for the characterization of various focal lesions. |
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Authors:
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J S Yu; K W Kim; B J Jo; M G Jeong; J K Kim; J K Hahm; J T Lee; H S Yoo |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Yonsei medical journal Volume: 41 ISSN: 0513-5796 ISO Abbreviation: Yonsei Med. J. Publication Date: 2000 Aug |
Date Detail:
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Created Date: 2000-09-28 Completed Date: 2000-09-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0414003 Medline TA: Yonsei Med J Country: KOREA (SOUTH) |
Other Details:
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Languages: eng Pagination: 459-67 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, Korea. yjsrad97@yumc.yonsei.ac.kr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Female Hepatic Artery / pathology Humans Image Enhancement* Liver / pathology* Liver Neoplasms / diagnosis, secondary Magnetic Resonance Imaging Male Middle Aged Time Factors |
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