| Territorial arterial spin labeling in the assessment of collateral circulation: comparison with digital subtraction angiography. | |
| | |
MedLine Citation:
|
PMID: 18845805 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND AND PURPOSE: Collateral circulation plays a vital role in patients with steno-occlusive disease, in particular for predicting stroke outcome. Digital subtraction angiography (DSA) is the gold standard for the assessment of collateral circulation, despite its invasive nature. Recently, the development of a new class of arterial spin labeling (ASL) methods allowed independent measurement of territorial flow information without the need for contrast media injection. Here, we compared combined territorial ASL (TASL) and MR angiography (MRA) against DSA in the assessment of collateral circulation. METHODS: Eighteen patients presenting with extra- or intracranial arterial steno-occlusive disease were recruited. All DSA studies were performed using a biplane angiography unit. MR imaging consisted of time-of-flight MRA and TASL, performed at 3T. Collateral circulation on both modalities was evaluated in consensus in a double-blinded manner by 3 neuroradiologists. RESULTS: Good agreement was found between DSA and TASL in the assessment of collateral flow: Cramer coefficient, V=0.53 (P<0.0001) and Contingency coefficient, C=0.67, with kappa=0.70 and kappa=0.72 in the assessment of flow and collaterals, respectively. TASL and DSA successfully evaluated 89% and 98% of the vessels, respectfully. Failure was linked to motion-related artifacts in TASL, and highly tortuous vessels in DSA. Generally, combined MRA-TASL was comparable to DSA in diagnostic quality. CONCLUSIONS: TASL provided radiological information comparable to DSA on collateral flow, with the advantage that it could be performed during routine MRI studies. TASL may provide insight on collateral perfusion in patients who may not otherwise be candidates for DSA, and may potentially replace it. |
| | |
Authors:
|
Soke Miang Chng; Esben Thade Petersen; Ivan Zimine; Yih-Yian Sitoh; C C Tchoyoson Lim; Xavier Golay |
Related Documents
:
|
12664125 - Magnetic resonance angiography of the peripheral arteries: current status. 9613565 - Usefulness of mr angiography in detection of persistent trigeminal arteries. 12720265 - Time-resolved contrast-enhanced magnetic resonance angiography in pediatric patients us... 7480695 - Renal vasculature in potential renal transplant donors: comparison of mr imaging and di... 15699625 - Spinal epidural abscess caused by brucellosis. two case reports. 9268075 - Prediction of pathological tumor volume in clinically localized prostate cancer: value ... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2008-10-09 |
Journal Detail:
|
Title: Stroke; a journal of cerebral circulation Volume: 39 ISSN: 1524-4628 ISO Abbreviation: Stroke Publication Date: 2008 Dec |
Date Detail:
|
Created Date: 2008-11-25 Completed Date: 2009-01-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0235266 Medline TA: Stroke Country: United States |
Other Details:
|
Languages: eng Pagination: 3248-54 Citation Subset: IM |
Affiliation:
|
Department of Neuroradiology, National Neuroscience Institute, Singapore. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Angiography, Digital Subtraction* Artifacts Carotid Artery, Internal / physiopathology, radiography Carotid Stenosis / complications, diagnosis, physiopathology, radiography Cerebral Infarction / etiology Cerebrovascular Circulation* Cerebrovascular Disorders / diagnosis*, physiopathology, radiography Collateral Circulation* Double-Blind Method Female Humans Ischemic Attack, Transient / etiology Magnetic Resonance Angiography Male Middle Aged Motion Predictive Value of Tests Spin Labels* |
| Chemical | |
Reg. No./Substance:
|
0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of fasting glycemia and regional cerebral perfusion in diabetic subjects: a study with techne...
Next Document: Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent i...