Document Detail

Termination of abnormal intrauterine pregnancies with intramuscular administration of dihomo 15 methyl prostaglandin F 2alpha.
MedLine Citation:
PMID:  990229     Owner:  NLM     Status:  MEDLINE    
A synthetic compound, 2a, 2b dihomo 15 (S) 15 methyl prostaglandin F 2 alpha methyl ester given 8-hourly by intramuscular injection was used to terminate pregnancies in 72 patients with a missed abortion, intrauterine fetal death, molar or anencephalic pregnancies. Treatment was successful in all cases. A 4 mg dose of loperamide given orally at 15 to 30 minutes before the injection of prostaglandin analogue prevented diarrhoea as a side effect.
S M Karim; S S Ratnam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  83     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1976 Nov 
Date Detail:
Created Date:  1977-01-29     Completed Date:  1977-01-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  885-9     Citation Subset:  AIM; IM    
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MeSH Terms
Abortion, Missed / drug therapy
Abortion, Therapeutic*
Anencephaly / drug therapy
Diarrhea / chemically induced,  drug therapy
Fetal Death / drug therapy
Hydatidiform Mole / drug therapy
Loperamide / therapeutic use
Pregnancy Complications / drug therapy*
Prostaglandins F / therapeutic use
Prostaglandins, Synthetic / administration & dosage,  adverse effects,  therapeutic use*
Uterine Neoplasms / drug therapy
Reg. No./Substance:
0/Prostaglandins F; 0/Prostaglandins, Synthetic; 53179-11-6/Loperamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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