Document Detail


Terminating prolonged refractory status epilepticus using ketamine.
MedLine Citation:
PMID:  20098301     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Refractory status epilepticus (RSE) is an emergent and difficult neurologic problem that is not uncommon in clinical practice. In this report, we describe a 23-year-old man whose RSE was refractory to standard antiepileptic drugs and barbiturates; it was successfully terminated only with intravenous ketamine. In this report, we evaluated and discuss the clinical and electroencephalographic effects under ketamine. This case and the rare cases of ketamine experience in RSE reported in the literature show that ketamine is potentially effective to use when treating patients with RSE. Further clinical trials are warranted, however.
Authors:
Cheng-Yang Hsieh; Pi-Shan Sung; Jing-Jane Tsai; Chin-Wei Huang
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical neuropharmacology     Volume:  33     ISSN:  1537-162X     ISO Abbreviation:  Clin Neuropharmacol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-26     Completed Date:  2010-08-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7607910     Medline TA:  Clin Neuropharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  165-7     Citation Subset:  IM    
Affiliation:
Department of Neurology, Sin Lau Hospital; and Institute of Biopharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anticonvulsants / therapeutic use*
Humans
Ketamine / therapeutic use*
Male
Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors
Status Epilepticus / drug therapy*
Treatment Outcome
Young Adult
Chemical
Reg. No./Substance:
0/Anticonvulsants; 0/Receptors, N-Methyl-D-Aspartate; 6740-88-1/Ketamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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