| Terminal ileum of patients who underwent colonoscopy: endoscopic, histologic and clinical aspects. | |
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MedLine Citation:
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PMID: 19578609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONTEXT: For the diagnosis of the diseases which affect the terminal ileum, the colonoscopy allows macroscopic evaluation and the performing of biopsies. Studies with criteria for the endoscopic and histological characterization of this segment are scarce and there are still some doubts about the need of biopsies in patients with normal ileoscopy. OBJECTIVE: Study the terminal ileum of patients who underwent colonoscopy considering: endoscopic and histological correlation; agreement between results of the initial histological evaluation and slides review, and the chance of subjects with normal ileoscopy with abdominal pain and/or chronic diarrhea to show histological alterations. METHODS: In a prospective study, 111 patients who presented smooth mucosa without enanthema in the endoscopic exam of the terminal ileum were selected. Biopsies of the ileal mucosa of such patients were performed, being the slides routinely examined and reviewed afterwards. RESULTS: The correlation between patients with normal ileoscopy and ileum with preserved histological architecture was of 99.1%. The agreement between initial histological evaluation and slides review calculated by the Kappa test was 0.21. In patients with abdominal pain and/or chronic diarrhea, the chance of showing histological alterations was 2.5 times higher than the others. CONCLUSIONS: The correlation between endoscopic and histological findings was high. The agreement between the initial histologic evaluation and slides review was not satisfactory. The chance of subjects with normal ileoscopy with abdominal pain and/or chronic diarrhea, showing histological alterations was higher in relation to the asymptomatic ones or with other symptoms, although the clinical importance of this datum was not evaluated. |
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Authors:
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Marcelo Maia Caixeta de Melo; Patrícia Maluf Cury; Luiz Sérgio Ronchi; Francisco de Assis Gonçalves-Filho; Geni Satomi Cunrath; João Gomes Netinho |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Arquivos de gastroenterologia Volume: 46 ISSN: 1678-4219 ISO Abbreviation: Arq Gastroenterol Publication Date: 2009 Apr-Jun |
Date Detail:
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Created Date: 2009-07-06 Completed Date: 2009-10-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 15310600R Medline TA: Arq Gastroenterol Country: Brazil |
Other Details:
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Languages: eng Pagination: 102-6 Citation Subset: IM |
Affiliation:
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Surgery Department, Medical School of São José do Rio Preto, São Paulo, Brazil. maiacaixeta@ig.com.br |
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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etiology Adolescent Adult Aged Aged, 80 and over Biopsy Chronic Disease Diarrhea / etiology Endoscopy, Gastrointestinal Female Humans Ileal Diseases / complications, pathology* Ileum / pathology Male Middle Aged Prospective Studies Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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