Document Detail


Term delivery following conservative treatment for villoglandular papillary adenocarcinoma of the uterine cervix: report of a case and analysis of the literature.
MedLine Citation:
PMID:  11330967     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Villoglandularpapillary adenocarcinoma (VPA) of the cervix is often indolent, and surgical treatment has a favorable outlook. Risk factors include depth of invasion, lymphovascular invasion, and the presence of other histologic types of cancer. CASE: An amputation of the cervical portio was required to satisfactorily resect a 2.5-cm ectocervical lesion in a 28-year-old nulligravida. A diagnosis of pure VPA with a depth of invasion less than 2 mm was established. During a subsequent pregnancy, second trimester ultrasound showed extreme effacement of her cervix and an abdominal cerclage was placed. The pregnancy continued until delivery of a healthy infant at 36 weeks. CONCLUSIONS: In cases of tumor invasion less than 3 mm, and in the absence of lymphovascular space involvement, extrauterine spread of pure VPA has not been described. When conservative treatment is planned, amputation of the cervical portio may be better suited than conization to the achievement of an adequate margin of resection. Cervical cerclage may be needed to offset the extensive cervical surgery.
Authors:
J S Hoffman; L Bazzurini; L Laird; J C Murphy; U Magriples; J Lewis
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Gynecologic oncology     Volume:  81     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-01     Completed Date:  2001-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  310-3     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Academic Press.
Affiliation:
Division Gynecologic Oncology, New Britain General Hospital, New Britain, CT 06052, USA.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma, Papillary / pathology,  surgery*
Adult
Female
Humans
Neoplasm Staging
Pregnancy
Pregnancy Complications, Neoplastic*
Uterine Cervical Neoplasms / pathology,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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