Document Detail


Terlipressin improves renal function in patients with cirrhosis and ascites without hepatorenal syndrome.
MedLine Citation:
PMID:  18027874     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: The vasopressin 1 receptor agonist terlipressin improves renal function and induces natriuresis in patients with cirrhosis and ascites without HRS. Vasoconstrictors may represent a novel future treatment modality for these patients.
Authors:
Aleksander Krag; Søren Møller; Jens H Henriksen; Niels-Henrik Holstein-Rathlou; Fin Stolze Larsen; Flemming Bendtsen
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  46     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-06     Completed Date:  2008-01-10     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1863-71     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Ascites / etiology
Double-Blind Method
Female
Glomerular Filtration Rate / drug effects
Hepatorenal Syndrome
Humans
Kidney / blood supply,  drug effects,  physiopathology*
Kidney Diseases / drug therapy*,  etiology
Liver Cirrhosis, Alcoholic / complications*
Lypressin / analogs & derivatives*,  pharmacology,  therapeutic use
Male
Middle Aged
Receptors, Vasopressin / drug effects
Recovery of Function
Vasoconstrictor Agents / pharmacology,  therapeutic use*
Chemical
Reg. No./Substance:
0/Receptors, Vasopressin; 0/Vasoconstrictor Agents; 14636-12-5/terlipressin; 50-57-7/Lypressin
Comments/Corrections
Comment In:
Hepatology. 2007 Dec;46(6):1685-7   [PMID:  18046716 ]
Hepatology. 2008 Aug;48(2):686   [PMID:  18666233 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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