| Teratological studies on collagen wound dressing (CAS) in mice. | |
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MedLine Citation:
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PMID: 7183770 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We subcutaneously injected collagen wound dressing (CAS) extracts equivalent to the area covering human body surface by 35 and 70%, respectively, into mouse dams from days 6 to 15 of pregnancy. No toxicity was observed in dams and no external, skeletal and visceral anomalies related to CAS treatment were observed in fetuses. It is, therefore, concluded that CAS extracts produces no teratogenesis after subcutaneous injection during organogenesis in mice. |
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Authors:
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U Takada; M Moriguchi; T Hata; A Yamamoto |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of toxicological sciences Volume: 7 Suppl 2 ISSN: 0388-1350 ISO Abbreviation: J Toxicol Sci Publication Date: 1982 Dec |
Date Detail:
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Created Date: 1983-08-11 Completed Date: 1983-08-11 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7805798 Medline TA: J Toxicol Sci Country: JAPAN |
Other Details:
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Languages: eng Pagination: 57-61 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Drug-Induced* Animals Bandages / adverse effects* Biological Dressings / adverse effects* Bone and Bones / abnormalities Collagen / toxicity* Female Fetus / drug effects Mice Mice, Inbred Strains Pregnancy |
| Chemical | |
Reg. No./Substance:
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9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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