Document Detail


Teratological risk evaluation and prevention of voluntary abortion.
MedLine Citation:
PMID:  16582865     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: Many women exposed to completely innocuous agents during pregnancy have a high perception of adverse effects to such an extent that they may interrupt their pregnancy. The objective of our study is to evaluate the importance of the perception of the risk level in making the decision to end the pregnancy and the relevance that a teratology consultation can have in preventing unmotivated terminations of pregnancy METHODS: We carried out a survey on 350 women in Rome who voluntarily interrupted their pregnancy to evaluate the prevalence due to presumed teratogen. Contemporarily we studied the pregnancy outcomes, the clinical, the psychological and the socio-economic factors of 142 women who contacted our Teratology Information Service (TIS) in the 1(st)trimester of pregnancy because suspected of teratogen exposure: 72 decided to terminate their pregnancy, whereas 70 were used as a control group. RESULTS: On 350 women who voluntarily interrupted their pregnancy, 4 cases (1.4%) reported exposure to a suspected teratogen, but our evaluation determined only 1 case. On 72 women decided to terminate their pregnancy and who contacted our TIS, after counselling 73% continued their pregnancy with respect to 97% of the control group. Those women who interrupted their pregnancy did so because of personal reasons independently to or the type of exposure or the risk attributed by us. CONCLUSIONS: From our data it appears that a percentage of voluntary abortions is related to suspected teratogen exposure and that TIS are effective in the prevention of this kind of voluntary abortions caused by groundless fears.
Authors:
M De Santis; G Straface; A F Cavaliere; B Cinque; B Carducci; A Caruso
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Minerva ginecologica     Volume:  58     ISSN:  0026-4784     ISO Abbreviation:  Minerva Ginecol     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-11-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400731     Medline TA:  Minerva Ginecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  91-9     Citation Subset:  IM    
Affiliation:
Telefono Rosso, Teratology Information Service, Department of Obstetrics and Gynecology, Sacro Cuore Catholic University, Rome, Italy. marcodesantis@rm.unicatt.it
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced*
Abortion, Induced / statistics & numerical data*
Adult
Female
Follow-Up Studies
Humans
Questionnaires
Retrospective Studies
Risk Assessment
Risk Factors
Teratogens
Chemical
Reg. No./Substance:
0/Teratogens

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