Document Detail

Teratoid carcinosarcoma of the ovary with prominent neuroectodermal differentiation.
MedLine Citation:
PMID:  11881739     Owner:  NLM     Status:  MEDLINE    
We present what we believe to be only the second report of ovarian teratoid carcinosarcoma. The patient, a 59-year-old woman, was admitted to hospital complaining of a pelvic mass and of abdominal fullness. Advanced ovarian cancer was diagnosed, and a tumorectomy was done. The tumor occupied the pelvis, and metastasis was found in the liver and spleen. The solid tumor was composed of chondrosarcoma, squamous cell carcinoma, adenocarcinoma and malignant neuroectodermal components, which contained ganglioneuroblastoma-like and medulloepithelioma-like areas. Immunohistochemically, the neuroectodermal cells were positive for both neural and epithelial markers. This ovarian tumor consisted of frankly malignant components, with prominent neuroectodermal elements mixed with epithelial and mesenchymal elements in an organoid fashion; a quite rare tumor.
A Tanimoto; N Arima; R Hayashi; T Hamada; Y Matsuki; Y Sasaguri
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology international     Volume:  51     ISSN:  1320-5463     ISO Abbreviation:  Pathol. Int.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2002-03-07     Completed Date:  2002-04-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9431380     Medline TA:  Pathol Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  829-32     Citation Subset:  IM    
Department of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Yahatanishi, Kitakyushu, Japan.
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MeSH Terms
Carcinosarcoma / chemistry,  secondary*,  surgery
Liver Neoplasms / secondary
Middle Aged
Neuroectodermal Tumors / chemistry,  secondary*
Ovarian Neoplasms / chemistry,  pathology*,  surgery
Splenic Neoplasms / secondary
Teratoma / chemistry,  secondary*,  surgery
Tumor Markers, Biological / analysis
Reg. No./Substance:
0/Tumor Markers, Biological

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