Document Detail

Teratogens associated with congenital contractures in humans and in animals.
MedLine Citation:
PMID:  7101197     Owner:  NLM     Status:  MEDLINE    
An evaluation of over 350 patients in a study of congenital contractures of the joints (arthrogryposis) included a review of family, pregnancy, and delivery histories for teratogenic exposures. Fifteen out of the total 350 patients studied had a possible teratogenic exposure: an infectious agent (viral or bacterial), maternal drug or toxin ingestion, chronic maternal neurologic or muscular illness, or a direct physical insult such as a structural uterine anomaly. Literature was reviewed for all human and animal cases reported with congenital contractures of the joints with an associated teratogenic insult. Those findings are discussed here.
J G Hall; S D Reed
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Teratology     Volume:  25     ISSN:  0040-3709     ISO Abbreviation:  Teratology     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-09-24     Completed Date:  1982-09-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0153257     Medline TA:  Teratology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  173-91     Citation Subset:  IM    
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MeSH Terms
Arthrogryposis / chemically induced,  etiology*
Bacterial Infections / complications*
Ethanol / toxicity
Infant, Newborn
Methocarbamol / toxicity
Muscular Dystrophies / complications
Myasthenia Gravis / complications
Plants, Toxic
Pregnancy Complications
Tetracycline / adverse effects
Virus Diseases / complications*
Grant Support
Reg. No./Substance:
0/Teratogens; 532-03-6/Methocarbamol; 60-54-8/Tetracycline; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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