Document Detail


Teratogenicity and maternal effects of Lactobacillus brevis KB290 in rats and rabbits.
MedLine Citation:
PMID:  21112368     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Lactobacillus brevis KB290 (KB290), a plant-derived probiotic lactic acid bacterium, improves gut health and stimulates immune function. Here we extensively investigated the teratogenicity of KB290 in rats and rabbits. We observed no adverse maternal or fetal effects and concluded that the no observable adverse effect level for maternal general toxicity, maintenance of pregnancy, and teratogenicity should be ⩾10(10)cfu/kg/day. Our results suggest that KB290 would be safe for pregnant females and their offspring.
Authors:
T Yakabe; H Takashima; M Kuwagata; M Fukao; S Kikuchi; N Yajima
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-11-26
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  -     ISSN:  1873-6351     ISO Abbreviation:  -     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2011-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Research Institute, Kagome Co., Ltd., Tochigi, Japan.
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