Document Detail

Tension-free primary closure with autologous platelet gel versus Vivostat- for the definitive treatment of chronic sacrococcygeal pilonidal disease.
MedLine Citation:
PMID:  20668329     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: A randomized clinical trial was performed in patients with chronic or recurrent pilonidal sinus (PS) comparing primary closure coupled with random application of in house autologous platelet gel or produced by means of Vivostat- in order to assess whether a standardized product had an impact on the wound healing process. PATIENTS AND METHODS: Between June 2006 and June 2009, 100 patients (82 males, 18 females: median age 30 years; range, 16-51 years) underwent wide excision of the pilonidal area with midline tension-free closure and were randomly given either the in house autologous platelet gel (Group 1) or the Vivostat- gel (Group 2). RESULTS: Group 2 patients had shorter wound healing time (8 vs. 10 days; p<0.0001), time to return to full activity (11 vs. 16 days: p<0.0001), less uncomplicated fluid collections (120 vs. 190 ml: p<0.0001), and fewer postoperative wound complications (1/50=2% vs. 5/50=10%, p<0.001). After a median follow-up of 21 months (range: 4-40 months), two recurrences were detected in Group 1. CONCLUSION: The standardized production of platelet gel by means of the Vivostat- system guarantees the reproducibility of the procedure and its use was correlated with an improved outcome, with a high degree of patient satisfaction and better cosmetic results.
Marco Gipponi; Giuliano Reboa; Tommaso Testa; Gabriella Giannini; Paolo Strada
Related Documents :
12495409 - Effect of electrical stimulation on chronic leg ulcer size and appearance.
15703519 - Primary and delayed closure after open irrigation and debridement of septic arthritis i...
9038269 - The effect of sartorius transposition on wound morbidity following inguinal-femoral lym...
2050719 - Preventing postoperative burn wound aspergillosis.
23552719 - Review: lower rather than higher tidal volume benefits ventilated patients without ards.
8064909 - A longitudinal study of resting energy expenditure in thermally injured patients.
24445629 - Increased glycemic variability in patients with elevated preoperative hba1c predicts ad...
10569169 - Long-term follow-up of anterior uveitis after cataract extraction and intraocular lens ...
14583929 - Heparins and mechanical methods for thromboprophylaxis in colorectal surgery.
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  In vivo (Athens, Greece)     Volume:  24     ISSN:  0258-851X     ISO Abbreviation:  In Vivo     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-07-29     Completed Date:  2010-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806809     Medline TA:  In Vivo     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  583-9     Citation Subset:  IM    
U.O.C. Chirurgia Generale, Colon-Retto-Ano, Azienda Ospedaliera Universitaria San Martino Genova, L.go R. Benzi, 10, 16132 Genoa, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adipose Tissue / surgery
Chronic Disease
Drainage / methods
Gels / therapeutic use*
Middle Aged
Pilonidal Sinus / surgery*
Platelet Transfusion / methods
Postoperative Complications / epidemiology
Surgical Flaps*
Surgical Wound Dehiscence
Transplantation, Autologous
Wound Healing
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Absence of CIP1/KIP1 Hypermethylation in Gastric Cancer Patients from Northern Brazil.
Next Document:  Efficacy of topical cyanoacrylates compared to topical silicone gel in the treatment of hypertrophic...