Document Detail


Tensile adhesion of type I collagen to titanium alloy and calcium phosphate coated surfaces with different roughness values.
MedLine Citation:
PMID:  12652029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of total joint arthroplasty is to reduce pain and restore function. Its success depends on the formation of a new bone that stabilizes the prosthesis. The proposed solution for this important problem is to have bio-coated implant surfaces which are more conductive to bone growth. Additionally, collagen has long been used as a matrix for medical applications, because of its biocompatibility and adaptability. In this study, a test method for measuring the tensile adhesion strength of collagen to titanium alloy and calcium phosphate coated surfaces with different roughness values was developed, in order to evaluate how well the collagen adheres to the metallic and bio-coated surfaces. A precision motion system was used to stretch gels that were adherent to the plate surfaces. The tests were done in DMEM solution. The adhesive strength between the collagen gel and plate was significantly higher for calcium phosphate coated surfaces. Adhesive strength was highest in the sample with the highest roughness value.
Authors:
Baris Ozerdem
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  Bio-medical materials and engineering     Volume:  12     ISSN:  0959-2989     ISO Abbreviation:  Biomed Mater Eng     Publication Date:  2002  
Date Detail:
Created Date:  2003-03-24     Completed Date:  2003-09-26     Revised Date:  2013-04-05    
Medline Journal Info:
Nlm Unique ID:  9104021     Medline TA:  Biomed Mater Eng     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  347-52     Citation Subset:  IM    
Affiliation:
Department of Mechanical Engineering, The Catholic University of America, Wahington, DC 20064, USA. ozerdem@likya.iyte.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Adsorption
Calcium Phosphates / chemistry*
Coated Materials, Biocompatible*
Collagen Type I / chemistry*
Elasticity
Hardness
Materials Testing
Stress, Mechanical
Surface Properties
Tensile Strength
Titanium / chemistry*
Chemical
Reg. No./Substance:
0/Calcium Phosphates; 0/Coated Materials, Biocompatible; 0/Collagen Type I; 0/alpha-tricalcium phosphate; 0/monocalcium phosphate; 0/tetracalcium phosphate; 12743-70-3/titanium alloy (TiAl6V4); 7440-32-6/Titanium; 97Z1WI3NDX/calcium phosphate; L11K75P92J/dicalcium phosphate anhydrous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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