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Tendovaginitis with arthritis, a new syndrome of chickens: isolation and characterization of an infectious agent.
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MedLine Citation:
PMID:  13263488     Owner:  NLM     Status:  OLDMEDLINE    
Abstract/OtherAbstract:
The findings with an infectious agent isolated from cases of tendovaginitis or arthritis of chickens were as follows:- Cultures, stains, and darkfield studies of material containing this agent for spirochetes, bacteria, and pleuropneumonia-like organisms were negative. The yolk sac was the preferred route of inoculation, all of the embryos dying in 4 to 12 days. The agent passed through a bacteria-retaining filter, but with a drop in titer. Antibiotic sensitivity tests revealed that the agent was most sensitive to the tetracycline antibiotics, less sensitive to chloromycetin, dihydrostreptomycin, and resistant to penicillin. From electron micrographs it was concluded that the agent is a rigid, dense, coccobacillus from 0.2 micro to 0.5 micro, in size. The agent produced a cytopathogenic effect in tissue cultures of chick heart fibroblasts. The agent had no gross effect on suckling or newly weaned mice, pigs, or guinea pigs. Reasons for suggesting that the agent is most similar to a rickettsia or possibly a large virus are discussed.
Authors:
J G LECCE; F G SPERLING; L HAYFLICK; W STINEBRING
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of experimental medicine     Volume:  102     ISSN:  0022-1007     ISO Abbreviation:  J. Exp. Med.     Publication Date:  1955 Oct 
Date Detail:
Created Date:  1956-12-01     Completed Date:  2003-05-01     Revised Date:  2010-09-21    
Medline Journal Info:
Nlm Unique ID:  2985109R     Medline TA:  J Exp Med     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  489-98     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Arthritis / complications*
Tenosynovitis / complications*
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Exp Med
ISSN: 0022-1007
ISSN: 1540-9538
Publisher: The Rockefeller University Press
Article Information
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Copyright © Copyright, 1955, by The Rockefeller Institute for Medical Research New York
Received Day: 6 Month: 6 Year: 1955
Print publication date: Day: 30 Month: 9 Year: 1955
Volume: 102 Issue: 4
First Page: 489 Last Page: 498
ID: 2136517
PubMed Id: 13263488

TENDOVAGINITIS WITH ARTHRITIS, A NEW SYNDROME OF CHICKENS: ISOLATION AND CHARACTERIZATION OF AN INFECTIOUS AGENT
J. G. Lecce
F. G. Sperling
L. Hayflick
W. Stinebring
From New Bolton Center, School of Veterinary Medicine and the Department of Microbiology, School of Medicine, University of Pennsylvania, Philadelphia


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