Document Detail

Tenascin expression in mucocutaneous diseases and related lesions of human oral mucosa.
MedLine Citation:
PMID:  8670022     Owner:  NLM     Status:  MEDLINE    
The expression of tenascin was assessed immunohistochemically. In normal oral mucosa, immunoreactivity for tenascin was seen either as a delicate line underlining the epithelium or in the stromal papillae. In oral lichen planus, a marked enhancement of tenascin immunoreactivity in the lamina propria was associated with focal infiltrates of inflammatory cells and seemed to reflect the intensity of inflammation. In lichenoid reactions in which only a sparse inflammatory infiltrate was present a band-like tenascin reactivity was seen. Oral psoriform reactions and chronic hyperplastic candidosis showed a prominent tenascin reaction in the connective tissue papillae among infiltrates of inflammatory cells. The results show that tenascin content is increased in oral mucocutaneous diseases and related lesions and that the abundance of tenascin reflects the intensity of the inflammatory reaction.
O Tiitta; M Luomanen; J Hietanen; I Virtanen
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of oral biology     Volume:  40     ISSN:  0003-9969     ISO Abbreviation:  Arch. Oral Biol.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-08-05     Completed Date:  1996-08-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0116711     Medline TA:  Arch Oral Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1039-45     Citation Subset:  D; IM    
Department of Anatomy, University of Helsinki, Finland.
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MeSH Terms
Candidiasis, Oral / genetics,  pathology
Chronic Disease
Connective Tissue / metabolism,  pathology
Epithelium / metabolism,  pathology
Gene Expression Regulation
Leukoplakia, Oral / genetics,  pathology
Lichen Planus, Oral / genetics,  pathology
Lichenoid Eruptions / genetics,  pathology
Mouth Diseases / genetics,  pathology*
Mouth Mucosa / metabolism,  pathology
Tenascin / analysis*,  genetics
Reg. No./Substance:

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