| Ten years experience of in-center thrice weekly long overnight hemodialysis. | |
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MedLine Citation:
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PMID: 19470659 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVES: Published studies suggest that longer hemodialysis (HD) sessions are associated with improved morbidity and mortality, but few centers offer long sessions. The Western Infirmary renal unit has offered long overnight hemodialysis (LOH) (6 to 7 h) thrice weekly since 1998. The aim of this study was to describe patients who chose LOH and compare outcomes with patients on conventional hours (4 to 5 h) HD. DESIGN, SETTINGS, PARTICIPANTS, & MEASUREMENTS: Patients who ever had LOH for three or more consecutive sessions were identified (n = 146). Indices of urea reduction ratio (URR), anemia, hyperphosphatemia, and predialysis BP (BP) control in a subgroup of all patients on LOH for at least 1 yr since 2004 were compared with age, sex, and diabetes-matched controls undergoing conventional duration HD. RESULTS: The mean age at the time of starting LOH was 51.8 yr and 74.7% started with a functioning arteriovenous fistula. Median duration of continuous LOH was 1.6 yr. Of those no longer on LOH, only 33.3% reverted to conventional hours HD (mean duration LOH 2.2 yr). When comparing LOH and conventional HD cohorts, there was increased URR and mean hemoglobin with a trend toward lower mean erythropoietin index. There was a trend toward fewer phosphate binder tablets but no difference in mean serum phosphate, BP, or number of prescribed antihypertensive medicines. CONCLUSIONS: LOH is a well tolerated hemodialysis option, associated with improved URR and better control of anemia. |
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Authors:
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Joanna Ruth Powell; Oyeniran Oluwaseun; Yook Mun Woo; Neal Padmanabhan; Eliyanachii Narasinghan; Carol Latta; Julie Tortolano; Alan G Jardine; Colin C Geddes |
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Publication Detail:
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Type: Journal Article Date: 2009-05-21 |
Journal Detail:
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Title: Clinical journal of the American Society of Nephrology : CJASN Volume: 4 ISSN: 1555-905X ISO Abbreviation: Clin J Am Soc Nephrol Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-04 Completed Date: 2009-08-27 Revised Date: 2010-09-27 |
Medline Journal Info:
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Nlm Unique ID: 101271570 Medline TA: Clin J Am Soc Nephrol Country: United States |
Other Details:
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Languages: eng Pagination: 1097-101 Citation Subset: IM |
Affiliation:
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Renal Unit (Level 7), Western Infirmary, Glasgow, United Kingdom. Joanna.Powell@ggc.scot.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anemia / metabolism, therapy* Blood Pressure Case-Control Studies Erythropoietin / blood Female Hemoglobins / metabolism Humans Hyperphosphatemia / drug therapy, metabolism Kidney Failure, Chronic / metabolism, therapy* Male Middle Aged Night Care* Patient Satisfaction* Phosphates / blood Renal Dialysis / methods* Urea / blood |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 0/Phosphates; 11096-26-7/Erythropoietin; 57-13-6/Urea |
| Comments/Corrections | |
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