| Ten-year survival and risk of relapse for testicular cancer: a EUROCARE high resolution study. | |
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MedLine Citation:
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PMID: 17222545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effective treatments for testicular cancer have been available since the 1970s, yet EUROCARE uncovered marked inter-country survival differences for this disease. To investigate these differences, we reviewed clinical records of 1350 testicular cancer cases diagnosed during 1987-1992 from 13 population-based cancer registries in nine European countries. Patients were followed up for life status and relapse. Ten-year observed survival was estimated by the Kaplan-Meier method. Cox multivariable analyses were performed separately for seminomas and non-seminomas. Overall, 66% of seminomas and 36% of non-seminomas were limited to the testis. Ten-year survival was 63% (Estonia) to 94% (Switzerland, Slovenia) for seminoma; 47% (Estonia) to 90% (Yorkshire, UK, The Netherlands) for non-seminoma. Multivariable analysis adjusted for country, age and stage showed that hazard ratios (HRs) of death differed little between western European registries, and were mainly attributable to differing stage at diagnosis. Significantly higher than reference HRs in Estonia and Poland suggest inadequacy or unavailability of treatments. |
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Authors:
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Milena Sant; Tiiu Aareleid; Maria Elisa Artioli; Franco Berrino; Jan Willem Coebergh; Marc Colonna; David Forman; Guy Hedèlin; Jadwiga Rachtan; Jean Michel Lutz; Renée Otter; Nicole Raverdy; Ivan Plesko I; Maja-Zakelj Primic; Giovanna Tagliabue |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't Date: 2007-01-11 |
Journal Detail:
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Title: European journal of cancer (Oxford, England : 1990) Volume: 43 ISSN: 0959-8049 ISO Abbreviation: Eur. J. Cancer Publication Date: 2007 Feb |
Date Detail:
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Created Date: 2007-02-05 Completed Date: 2007-05-01 Revised Date: 2009-02-12 |
Medline Journal Info:
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Nlm Unique ID: 9005373 Medline TA: Eur J Cancer Country: England |
Other Details:
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Languages: eng Pagination: 585-92 Citation Subset: IM |
Affiliation:
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Department of Preventive and Predictive Medicine, Unit of Etiological Epidemiology and Prevention, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian 1, Milan I-20133, Italy. milena.sant@istitutotumori.mi.it |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Europe / epidemiology Humans Male Middle Aged Neoplasm Recurrence, Local / mortality* Registries Risk Factors Seminoma / mortality* Survival Analysis Testicular Neoplasms / mortality* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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