Document Detail

Ten-year survey of positive blood cultures among admissions to a neonatal intensive care unit.
MedLine Citation:
PMID:  3333254     Owner:  NLM     Status:  MEDLINE    
A 10-year survey of positive blood cultures was conducted among 6,616 infants admitted to an intensive care unit from 1974-1983. Group B streptococci (59) and E. coli (32) were the most common pathogenic organisms isolated from the early onset group (less than 72 hours of age). The percentage of infants with bacteremia, the birth weight distribution of infected infants, and the organisms isolated did not change in the early onset group throughout the study period. Coagulase negative staphylococci (471), S. aureus (126), E. coli (33), Klebsiella sp. (30), and enterococci (30) were the most frequent organisms isolated from the late onset group. The frequency of infection in the late onset group did not change as a function of time but was associated with decreasing birth weight during the study period. Methicillin and gentamicin resistance among coagulase negative staphylococci preceded that of S. aureus by one to three years, suggesting interspecies transfer of bacterial resistance among staphylococci. The data indicate that whereas the epidemiology of early-onset septicemia has remained relatively stable during the study period, the incidence of late onset bacteremia is increasing with improved survival rates of low birth weight infants. Antibiotic administration in the late onset group should include consideration of hospital-acquired, multiply antibiotic resistant organisms as well as maternally-acquired bacterial flora.
R T Hall; C G Kurth; S L Hall
Related Documents :
3911724 - A national survey of severe group b streptococcal infections in neonates and young infa...
768844 - Obstetric observations in eleven cases of neonatal sepsis due to the group b beta hemol...
21210254 - Role of hemocoagulase in pulmonary hemorrhage in preterm infants: a systematic review.
7045234 - Association between maternal gm allotype and neonatal septicaemia with group b streptoc...
23566294 - Does advanced maternal age confer a survival advantage to infants born at early gestation?
21169644 - Early rescue administration of surfactant and nasal continuous positive airway pressure...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  7     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  1987  
Date Detail:
Created Date:  1989-03-03     Completed Date:  1989-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  122-6     Citation Subset:  IM    
Children's Mercy Hospital, University of Missouri Kansas City School of Medicine.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood / microbiology
Cross Infection / etiology,  microbiology
Drug Resistance, Microbial
Escherichia coli Infections / etiology,  microbiology*
Infant, Newborn
Intensive Care Units, Neonatal*
Microbial Sensitivity Tests
Penicillin Resistance
Sepsis / etiology,  microbiology*
Staphylococcal Infections / etiology,  microbiology*
Streptococcal Infections / etiology,  microbiology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Antihistamines in asthma.
Next Document:  Organic solvents inhibit the mutagenicity of promutagens dimethylnitrosamine and methylbutylnitrosam...