Document Detail


Temporary elimination of orthostatic hypotension by norepinephrine infusion.
MedLine Citation:
PMID:  22983778     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A cardinal manifestation of chronic autonomic failure is neurogenic orthostatic hypotension (OH), which often is associated with supine hypertension, posing a therapeutic dilemma. We report here success in a first step toward development of a "prosthetic baroreceptor system" to maintain blood pressure during orthostasis without worsening supine hypertension. In all of four patients with neurogenic OH, titrated i.v. NE infusion kept directly recorded intra-arterial pressure at or above baseline during progressive head-up tilt. We conclude that titrated i.v. NE infusion temporarily eliminates OH.
Authors:
David S Goldstein; Latoya Sewell; Courtney Holmes; Sandra Pechnik; André Diedrich; David Robertson
Related Documents :
23540898 - Zero drift of intraventricular and subdural intracranial pressure monitoring systems.
3025918 - Effect of 24-hour preservation with oxygen free radical scavengers on isolated-perfused...
23580598 - Mechanisms of causal interaction between short-term rr interval and systolic arterial p...
7363928 - Perfusion-fixation of the heart and its conduction system for ultrastructural studies.
20877698 - Recent advance in patient monitoring.
9267948 - Insights into the increased oxygen demand during chest physiotherapy.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-16
Journal Detail:
Title:  Clinical autonomic research : official journal of the Clinical Autonomic Research Society     Volume:  -     ISSN:  1619-1560     ISO Abbreviation:  Clin. Auton. Res.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9106549     Medline TA:  Clin Auton Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892-1620, USA, goldsteind@ninds.nih.gov.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Seeking Connections, Creating Movement: The Power of Altruistic Action.
Next Document:  Management of gastric perforations during laparoscopic gastric banding.