| Temporal trends in sudden cardiac arrest: a 25-year emergency medical services perspective. | |
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MedLine Citation:
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PMID: 12756155 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Little is known about temporal trends in survival and prognostic characteristics of patients with out-of-hospital cardiac arrest treated by emergency medical services (EMS). We hypothesized that an evolving combination of beneficial and adverse factors may contribute to temporal patterns of survival. METHODS AND RESULTS: We evaluated a population-based cohort of EMS-treated adult patients with cardiac arrest (n=12 591) from 1977 to 2001 in King County, Washington. Time was grouped into an initial 5-year period and 5 successive 4-year periods. We sought to determine the potential impact of temporal changes in prognostic factors typically beyond EMS control termed "fate" factors (for example, patient age) and factors implemented by EMS termed "program" factors (programs of dispatcher-assisted cardiopulmonary resuscitation and basic life support defibrillation). Several characteristics associated with survival changed over time. Observed survival did not change over time among all patients with cardiac arrest (OR=0.98 [0.95, 1.01], trend for each successive time period) and improved over time among patients with witnessed ventricular fibrillation (OR=1.05 [1.01, 1.09]). In models that included all patients with cardiac arrest and controlled for fate factors, advancing time period was associated with an increase in survival (OR=1.08 [1.05, 1.11]). Conversely, in models that controlled for program factors, advancing time period was associated with a decrease in survival (OR=0.95 [0.93, 0.98]). Results were similar among patients with witnessed ventricular fibrillation. CONCLUSIONS: The static temporal pattern of survival from cardiac arrest appeared to result from an evolving balance of prognostic factors. Programs implemented by EMS appeared to counter adverse temporal trends in prognostic factors typically beyond EMS control. |
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Authors:
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Thomas D Rea; Mickey S Eisenberg; Linda J Becker; John A Murray; Thomas Hearne |
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Publication Detail:
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Type: Journal Article Date: 2003-05-19 |
Journal Detail:
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Title: Circulation Volume: 107 ISSN: 1524-4539 ISO Abbreviation: Circulation Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-06-10 Completed Date: 2003-06-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: United States |
Other Details:
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Languages: eng Pagination: 2780-5 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, University of Washington, Seattle, USA. rea123@u.washington.edu |
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Cardiopulmonary Resuscitation / statistics & numerical data, trends Cohort Studies Electric Countershock Emergency Medical Services / statistics & numerical data*, trends* Female Heart Arrest / diagnosis, epidemiology*, therapy Humans Logistic Models Male Middle Aged Odds Ratio Prognosis Survival Analysis Time Factors Washington / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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