Document Detail

Temporal and spatial trends of perfluorinated compounds in ringed seal (Phoca hispida) from Greenland.
MedLine Citation:
PMID:  16245810     Owner:  NLM     Status:  MEDLINE    
Perfluorinated compounds (PFCs), such as perfluorooctane sulfonate (PFOS) and related compounds, have been identified as global pollutants and have shown their bioaccumulation into higher trophic levels in the food chain. PFCs have been found in remote areas far from sources, such as the Arctic. In this study spatial and temporal trends in the concentrations of selected PFCs were measured using archived liver samples of ringed seal (Phoca hispida) from East and West Greenland. The samples were collected in four different years at each location, between 1986 and 2003 in East Greenland and between 1982 and 2003 in West Greenland. PFOS was the major contributor to the burden of PFCs in samples, followed by perfluoroundecanoic acid (PFUnA). Perfluorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA) were also detected in most samples. Perfluorohexane sulfonate (PFHxS) and perfluorooctane sulfonamide (PFOSA) were only found sporadically. Perfluorooctanoic acid was not found in detectable concentrations in any sample. Regression analysis of logarithmic transformed PFOS, PFDA, and PFUnA median concentrations indicated a significant temporal trend with increasing concentrations at both locations. A spatial trend in PFOS concentrations (ANOVA, p < 0.0001) was observed between the two sampling locations, with significantly higher concentrations in seals from East Greenland.
Rossana Bossi; Frank F Riget; Rune Dietz
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental science & technology     Volume:  39     ISSN:  0013-936X     ISO Abbreviation:  Environ. Sci. Technol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-25     Completed Date:  2006-06-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0213155     Medline TA:  Environ Sci Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7416-22     Citation Subset:  IM    
National Environmental Research Institute, Frederiksborgvej 399, 4000-Roskilde, Denmark.
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MeSH Terms
Analysis of Variance
Chromatography, Liquid
Environmental Monitoring / statistics & numerical data*
Environmental Pollutants / analysis*,  pharmacokinetics*
Fluorocarbons / analysis*,  pharmacokinetics*
Liver / metabolism
Mass Spectrometry
Phoca / metabolism*
Regression Analysis
Reg. No./Substance:
0/Environmental Pollutants; 0/Fluorocarbons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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