Document Detail


Temporal relationship between pauses in nasal airflow and desaturation in preterm infants.
MedLine Citation:
PMID:  8860072     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Physiological recordings were undertaken to study the temporal relationship between apnea, defined as pauses in nasal airflow (PNA), and desaturation in preterm infants. Seventeen infants with a history of apnea of prematurity were studied on 21 occasions. Median (range) birthweight was 1,180 g (575-2,475) and gestation was 30 weeks (26-33). Median age at time of study was 10 days (range, 2-52). Arterial beat to beat oxygen saturation (SaO(2)), photoplethysmographic waveform, electrocardiogram, abdominal and ribcage breathing movements, and nasal airflow were recorded. Falls in SaO(2) > or = 3% occurring during or after a PNA > or = 4 seconds were recorded. Episodes of periodic breathing were excluded from this analysis. Four hundred and sixteen episodes of PNA and desaturation were analyzed. Application of a definition of "outliers" for non-parametric data suggested an association when the desaturation occurred up to 7.20 seconds after the end of the PNA for infants nursed in air. For infants on oxygen treatment, a temporal association was suggested when desaturation occurred up to 9.76 seconds after the end of PNA.
Authors:
S L Watkin; S A Spencer; A Pryce; D P Southall
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  21     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1997-02-19     Completed Date:  1997-02-19     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  171-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, North Staffordshire Hospital, Stoke on Trent, Staffordshire, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Apnea / physiopathology*
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / physiopathology*
Oximetry
Oxygen / metabolism*
Oxygen Inhalation Therapy
Statistics, Nonparametric
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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