Document Detail


Temporal profile of the directional tuning of the discharge of dorsal premotor cortical cells.
MedLine Citation:
PMID:  9601655     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examined the directional modulation of dorsal premotor (PMd) cells as a function of time in an instructed delay, reaching task that systematically varied direction and accuracy constraints. In two monkeys, the activity of 150 PMd cells was recorded and the preferred direction (PD) of the firing as a function of time, the PD trajectory, was calculated. Forty-one cells had nearly continuous significant directional tuning of at least 1 s duration (mean duration 1694 +/- 754 ms) that began in the instructed delay period and continued into the movement period. The PD gradually changed in time (mean change of 47.7 +/- 40.8 degrees), a change best described as a rotation. The change in the directional tuning as a function of time is consistent with the hypothesis that the PMd plays a role in the non-standard mapping of sensory stimuli into motor commands.
Authors:
C R Mason; M T Johnson; Q G Fu; J E Gomez; T J Ebner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neuroreport     Volume:  9     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-08-13     Completed Date:  1998-08-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  989-95     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University of Minnesota, Minneapolis 55455, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Electromyography
Evoked Potentials, Motor / physiology*
Female
Macaca mulatta
Motor Cortex / cytology,  physiology*
Movement / physiology*
Reaction Time / physiology*
Reproducibility of Results
Grant Support
ID/Acronym/Agency:
NS31530/NS/NINDS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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