Document Detail


Temporal pattern of locomotor activity recuperation after administration of propofol in Japanese quail (Coturnixcoturnixjaponica).
MedLine Citation:
PMID:  21724216     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The present study evaluates the organization and complexity of the temporal pattern of locomotion after an acute administration of propofol in Japanese quail by using traditional and fractal analysis. Birds were administered with propofol 0, 10, 20, 40 or 80mg/kg. Ten min after administration, they were placed in an open-field apparatus and their locomotor activity was recorded during 45min at a resolution of 0.5s. A significant dose dependant increase in the latency to initiate ambulation was observed for doses of 20, 40 and 80mg/kg when compared to the control group. A rapid recuperation of normal locomotor activity was observed after sedation with 20mg/kg. Birds administered with propofol 40mg/kg showed signs of recuperation of normal locomotion after 30 and 40min (males and females, respectively) of propofol administration, that was not observed in quail treated with propofol 80mg/kg. Our results suggest that depending on the dose, propofol administration in quail may allow full locomotor recovery of a sedative/anesthetic dose as early as 30min post-administration.
Authors:
J M Kembro; D A Guzman; M A Perillo; R H Marin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-1
Journal Detail:
Title:  Research in veterinary science     Volume:  -     ISSN:  1532-2661     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401300     Medline TA:  Res Vet Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Instituto de Ciencia y Tecnología de los Alimentos, Argentina; Cátedra de Química Biológica and Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Córdoba X5016GCA, Argentina.
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