| Temporal lobe volume in disorders with psychotic features. | |
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MedLine Citation:
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PMID: 18405073 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Since early neuropathological findings, temporal lobe has been related to the pathophysiology of some disorders with psychotic features. The aim of this study was to compare temporal lobe volumes and asymmetry differences in patients with schizophrenia, schizoaffective and bipolar disorders, disorders that cover the whole psychotic spectrum. Temporal lobe volumes were estimated using high resolution magnetic resonance imaging in 60 subjects, 15 subjects in each patient and one healthy volunteer (control) group. There are no statistically significant differences in temporal lobe volumes among patient and control groups. Comparison of left and right temporal lobes shows that left temporal lobes are smaller than right temporal lobes, however this difference reaches statistical significance only in groups of patients with schizoaffective and bipolar disorders. Overall temporal lobe volume may be less informative in respect to neuropathology of disorders with psychotic features than volumes of specific temporal lobe structures, in particular medial temporal lobe structures. |
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Authors:
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Elizabeta Radonić; Neven Henigsberg; Marko Rados; Ninoslav Mimica; Vera Folnegović-Smalc |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Collegium antropologicum Volume: 32 Suppl 1 ISSN: 0350-6134 ISO Abbreviation: Coll Antropol Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-04-14 Completed Date: 2008-05-01 Revised Date: 2009-02-04 |
Medline Journal Info:
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Nlm Unique ID: 8003354 Medline TA: Coll Antropol Country: Croatia |
Other Details:
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Languages: eng Pagination: 139-42 Citation Subset: IM |
Affiliation:
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Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia. eradonic@hiim.hr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bipolar Disorder / pathology* Case-Control Studies Female Humans Male Middle Aged Schizophrenia / pathology* Temporal Lobe / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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