| Temporal lobe resection for refractory temporal lobe epilepsy at Auckland Hospital. | |
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MedLine Citation:
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PMID: 19966878 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To analyse the long-term outcome of patients who underwent temporal lobe resection for intractable temporal lobe epilepsy at Auckland Hospital. METHODS: We performed a retrospective analysis of 176 patients who underwent temporal lobe resection at Auckland Hospital, New Zealand between 1987 and 2007. We had at least 1 year of follow-up on 174 patients. RESULTS: Overall 98/174 (56%) individuals were seizure-free at 1 year (Engel Class 1) with a marked improvement in quality of life. A further 61/174 (35%) had rare seizures or had significant improvement in seizure frequency (Engel Classes II or III). At last follow up (mean 4.3 years) 95/174 (55%) were seizure-free (Engel Class 1). Hippocampal sclerosis was the pathological finding in 129 patients. Surgical complications included 2 (1.1%) deaths, while 6 (3.4%) patients had symptomatic visual field defects, and 8 (4.5%) had other permanent neurological problems. A further 18 (10.3%) patients had temporary complications including infection, pulmonary embolus, and aseptic meningitis. New psychological symptoms occurred during the first year after surgery in 52% of 114 patients for whom we had detailed psychiatric assessments. CONCLUSION: Temporal lobe resection is effective in controlling medically intractable seizures, but there are potentially serious complications that need to be considered when counselling patients for such a procedure. |
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Authors:
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Ravi Suppiah; Edward Mee; Elizabeth B Walker; Lynair Roberts; Gregory Finucane; Peter S Bergin |
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Publication Detail:
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Type: Journal Article Date: 2009-10-30 |
Journal Detail:
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Title: The New Zealand medical journal Volume: 122 ISSN: 1175-8716 ISO Abbreviation: N. Z. Med. J. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-12-07 Completed Date: 2010-01-06 Revised Date: 2010-10-22 |
Medline Journal Info:
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Nlm Unique ID: 0401067 Medline TA: N Z Med J Country: New Zealand |
Other Details:
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Languages: eng Pagination: 47-56 Citation Subset: IM |
Affiliation:
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Department of Neurology, Auckland City Hospital, Auckland, New Zealand. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anterior Temporal Lobectomy* / adverse effects Epilepsy, Temporal Lobe / pathology, surgery* Female Humans Male New Zealand Postoperative Complications Quality of Life Retrospective Studies Treatment Outcome |
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