Document Detail


Temporal lobe epilepsy: clinical semiology and age at onset.
MedLine Citation:
PMID:  15929909     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to define the clinical semiology of seizures in temporal lobe epilepsy according to the age at onset. We analyzed 180 seizures from 50 patients with medial or neocortical temporal lobe epilepsy who underwent epilepsy surgery between 1997-2002, and achieved an Engel class I or II outcome. We classified the patients into two groups according to the age at the first seizure: at or before 17 years of age and 18 years of age or older. All patients underwent intensive video-EEG monitoring. We reviewed at least three seizures from each patient and analyzed the following clinical data: presence of aura, duration of aura, ictal and post-ictal period, clinical semiology of aura, ictal and post-ictal period. We also analyzed the following data from the clinical history prior to surgery: presence of isolated auras, frequency of secondary generalized seizures, and frequency of complex partial seizures. Non-parametric, chi-square tests and odds ratios were used for the statistical analysis. There were 41 patients in the "early onset" group and 9 patients in the "later onset" group. A relationship was found between early onset and mesial temporal lobe epilepsy and between later onset and neocortical temporal lobe epilepsy (p = 0.04). The later onset group presented a higher incidence of blinking during seizures (p = 0.03), a longer duration of the post-ictal period (p = 0.07) and a lower number of presurgical complex partial seizures (p = 0.03). The other parameters analyzed showed no significant differences between the two groups. We conclude that clinical and semiological differences exist between patients with temporal lobe epilepsy according to the age at onset. [Published with video sequences].
Authors:
Vicente Villanueva; José Maria Serratosa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Epileptic disorders : international epilepsy journal with videotape     Volume:  7     ISSN:  1294-9361     ISO Abbreviation:  Epileptic Disord     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-02     Completed Date:  2006-07-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100891853     Medline TA:  Epileptic Disord     Country:  France    
Other Details:
Languages:  eng     Pagination:  83-90     Citation Subset:  IM    
Affiliation:
Neurology Department, Fundacion Jimenez Diaz, Madrid, Spain. vevillanuevah@yahoo.es
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age of Onset
Blinking*
Child
Child, Preschool
Electroencephalography*
Epilepsy, Complex Partial / pathology*
Epilepsy, Temporal Lobe / pathology*
Female
Humans
Infant
Male
Preoperative Care
Video Recording

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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