Document Detail

Temporal lobe epilepsy after refractory status epilepticus: an illustrative case and review of the literature.
MedLine Citation:
PMID:  22953058     Owner:  NLM     Status:  PubMed-not-MEDLINE    
New onset refractory status epilepticus (NORSE) is a relatively newly defined disease entity, where otherwise healthy individuals develop unrelenting seizures that do not respond to conventional anticonvulsant therapy and may require months of therapy with anesthetic drugs. We have described a case of NORSE who subsequently developed mesial temporal lobe sclerosis (MTS) and recurrent temporal lobe seizures. We discuss the possible pathophysiological mechanisms by which refractory seizures may contribute to the development of temporal lobe epilepsy (TLE).
J Gordon Boyd; Derek B Debicki; G Bryan Young
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Publication Detail:
Type:  Journal Article     Date:  2012-04-10
Journal Detail:
Title:  Epilepsy research and treatment     Volume:  2012     ISSN:  2090-1356     ISO Abbreviation:  Epilepsy Res Treat     Publication Date:  2012  
Date Detail:
Created Date:  2012-09-06     Completed Date:  2012-09-06     Revised Date:  2013-03-07    
Medline Journal Info:
Nlm Unique ID:  101576602     Medline TA:  Epilepsy Res Treat     Country:  United States    
Other Details:
Languages:  eng     Pagination:  209701     Citation Subset:  -    
Division of Critical Care Medicine, Kingston General Hospital, Queen's University, Kingston, ON, Canada K7L 2V7.
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