Document Detail

Temporal hypoperfusion assessed by cerebral blood flow SPECT and long-term clinical outcome in patients with eating disorders.
MedLine Citation:
PMID:  19851171     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the relationship between temporal hypoperfusion in the acute phase of patients with eating disorders and the long-term clinical outcome. METHOD: Brain perfusion was studied using Tc-99m HMPAO SPECT in 17 patients with eating disorders (ED) and compared with 12 controls (C). Semiquantitative analysis was carried out by left/right indexes. Clinical records were reviewed 15 years later and the patients were classified into 2 groups: bad outcome in 10 patients and good outcome in 4. The results of the basal SPECT were compared with the clinical outcome. RESULTS: The mean of the differences of temporal perfusion in the lower slice was 0.1476 +/- 0.1121 in ED and 0.03 +/- 0.019 in C (P < 0.001). Comparisons between C and bad outcome showed a significant difference (P < 0.01). There was no significant difference between good outcome and C. CONCLUSIONS: The temporal hypoperfusion in the acute phase of patients with ED showed a correlation with the long-term clinical outcome and suggested a prognostic value of temporal hypoperfusion.
Julio F Jim??nez-Bonilla; Remedios Quirce; Ignacio Banzo; Isabel Mart??nez-Rodr??guez; Aurora Sainz-Esteban; Humberto Portilla; Jos?? Manuel Carril
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  34     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-23     Completed Date:  2009-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  768-72     Citation Subset:  IM    
Department of Nuclear Medicine, Hospital Universitario Marqu??s de Valdecilla, Universidad de Cantabria, Santander, Cantabria, Espa??a.
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MeSH Terms
Cerebrovascular Circulation / physiology*
Eating Disorders / physiopathology,  radionuclide imaging*,  therapy*
Perfusion Imaging / methods*
Temporal Lobe / physiopathology*,  radionuclide imaging*
Time Factors
Tomography, Emission-Computed, Single-Photon / methods*
Treatment Outcome

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