Document Detail

Temporal fat pad sign during corticosteroid treatment.
MedLine Citation:
PMID:  7436647     Owner:  NLM     Status:  MEDLINE    
Hypercortisolism alters the distribution of body fat, causing truncal obesity, moon facies, buffalo hump, and other localized fatty deposits. In a patient with a mixed collagen vascular disease (overlap syndrome), who received high systemic doses of prednisone, prominent painless bitemporal masses developed in association with moon facies. Punch biopsy specimens of the lesion disclosed normal adipose tisue. This unappreciated feature of hypercortisolism is described, and other clinical manifestations of glucocorticoid excess involving fat tissue are reviewed briefly.
N L Gottlieb
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of internal medicine     Volume:  140     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-01-29     Completed Date:  1981-01-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1507-8     Citation Subset:  AIM; IM    
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MeSH Terms
Adipose Tissue / drug effects*
Face* / drug effects
Mixed Connective Tissue Disease / drug therapy
Prednisone / adverse effects*
Grant Support
Reg. No./Substance:

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