Document Detail


Temporal bone study of trisomy 13 syndrome.
MedLine Citation:
PMID:  18090865     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The temporal bones of a 23-week-old female who had multiple congenital anomalies and bilateral hearing loss with trisomy 13 syndrome were evaluated under light microscopy. In the left cochlea, spiral ganglion cells and cochlear nerve fibers are absent. In the right ear, an abnormal branch of the singular nerve passes between the utricle and lateral semicircular canals and separates the two portions, one to the flattened crista of the lateral semicircular canal, the other to the utricular macula. This is a rare report describing a patient with abnormalities in three nerves, including the facial, vestibular, and cochlear nerves.
Authors:
Hisaki Fukushima; Patricia A Schachern; Sebahattin Cureoglu; Michael M Paparella
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Laryngoscope     Volume:  118     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-04     Completed Date:  2008-04-24     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  506-7     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA.
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MeSH Terms
Descriptor/Qualifier:
Chromosomes, Human, Pair 13*
Female
Humans
Infant
Temporal Bone / pathology*
Trisomy*
Grant Support
ID/Acronym/Agency:
P30 DC4660/DC/NIDCD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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