| Temporal behavior of intraarticular gadolinium. | |
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MedLine Citation:
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PMID: 11584223 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: As imaging delays during MR arthrography can result in suboptimal studies and potential pitfalls in diagnosis, we sought to evaluate the temporal behavior of intraarticular Gd-DTPA. METHOD: We prospectively studied four shoulders, four knees, and four hips. Two of each group received either an intraarticular injection of 3 mmol/L Gd-DTPA and iodinated contrast medium or 2 mmol/L Gd-DTPA and 0.9% saline. We measured contrast-to-noise ratio (CNR) and joint distention on serial T1-weighted sequences. Retrospectively, we measured CNR and imaging delays in 31 MR arthrography patients (20 shoulders, 7 knees, and 4 hips). RESULTS: In the shoulder, maximal CNR and joint distention occurred at 15 min. CNR decreased 53% by 1 h. In the knee, maximal distention occurred at 1 h, whereas CNR peaked at 2.75 h and then declined 20 and 86% by 3.5 and 6.25 h, respectively. In the hip, peak CNR and distention occurred at 0.5 h. CNR declined 53% by 2 h. Both contrast mixtures yielded similar results. CONCLUSION: MR arthrography may tolerate imaging delays of 1 h for the shoulder, 2 h for the hip, and 3.5 h for the knee. |
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Authors:
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S C Wagner; M E Schweitzer; D Weishaupt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 25 ISSN: 0363-8715 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2001 Sep-Oct |
Date Detail:
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Created Date: 2001-10-03 Completed Date: 2001-10-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 661-70 Citation Subset: IM |
Affiliation:
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Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chelating Agents / administration & dosage, diagnostic use Female Gadolinium / administration & dosage, diagnostic use, pharmacokinetics* Humans Joint Diseases / radionuclide imaging* Magnetic Resonance Imaging / methods Male Pentetic Acid / administration & dosage, diagnostic use Prospective Studies Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Chelating Agents; 67-43-6/Pentetic Acid; 7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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