Document Detail

Temporal aspects of the effects of cooling on responses of single auditory nerve fibers.
MedLine Citation:
PMID:  9745957     Owner:  NLM     Status:  MEDLINE    
During an investigation of the effects of cochlear cooling on frequency tuning and input/output relations of single auditory nerve fibers in gerbil (Ohlemiller and Siegel (1994) Hear. Res. 80, 174-190), cooling-related changes in post-stimulus time histogram (PSTH) shape and phase-locking to tonebursts were characterized in a small sample of neurons. Local cochlear cooling by 5-10 degrees C below normal core temperature did not alter overall PSTH shape, although some evidence was found for a reduction in the time constants of rapid and short term rate adaptation. The relative contributions of rapid and short term response components appeared unaltered. Effects of cooling on phase-locking were assessed by calculating the synchronization index for responses to intense ( > 70 dB SPL) tonebursts at 0.5, 1.0, and 2.0 kHz. Synchronization filter functions exhibited modest reductions in both magnitude and the upper frequency limit of phase-locking. The effects of cooling on the temporal character of responses appear distinct from those of a simple reduction in stimulus intensity. Results are interpreted in terms of cooling-related changes in responses of cochlear hair cells and afferent neurons, and suggest that temperature artifacts are unlikely to underlie reported species differences in PSTH shape and phase-locking.
K K Ohlemiller; J H Siegel
Related Documents :
25013107 - Fine-tuned echolocation and capture-flight of myotis capaccinii when facing different s...
4123917 - Occurrence and ultrastructure of a variant (rho) form of mycoplasma.
12851577 - The collagen fibers of the anteroinferior capsulolabrum have multiaxial orientation to ...
18066287 - Light-induced specular-reflectivity suppression at a gallium/silica interface.
14960117 - Stimulation artifact in surface emg signal: effect of the stimulation waveform, detecti...
18717387 - Absolute localization of vibrotactile stimuli on the torso.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Hearing research     Volume:  123     ISSN:  0378-5955     ISO Abbreviation:  Hear. Res.     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-11-30     Completed Date:  1998-11-30     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7900445     Medline TA:  Hear Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  78-86     Citation Subset:  IM    
Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acoustic Stimulation
Cochlea / physiology*
Cold Temperature*
Nerve Fibers / physiology*
Vestibulocochlear Nerve / physiology*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of high sound levels on responses to the vowel "eh" in cat auditory nerve.
Next Document:  Onset of basilar membrane non-linearity reflected in cubic distortion tone input-output functions.