Document Detail

Temporal Trends in Peritonitis Rates, Microbiology and Outcomes: The Major Clinical Complication of Peritoneal Dialysis.
MedLine Citation:
PMID:  22572743     Owner:  NLM     Status:  Publisher    
Peritonitis remains a common complication of peritoneal dialysis (PD). The aim of this study was to analyze, in a PD center, long-term temporal trends in peritonitis rates, microbiology and outcomes. We treated 588 cases of peritonitis that occurred during 11,833.6 months at risk. Y-set and twin-bag disconnecting systems were introduced in 1990, mupirocin at the exit site in 2000 and fluconazole prophylaxis in 2005. Vancomycin and ceftazidime were the empiric protocol. Global and 5-year cohort rates were expressed as episodes/patient-year (ep/p-y). A global peritonitis rate reduction was found from 1.02 to 0.47 ep/p-y (p = 0.008). Poisson analyses performed in each of the subgroups of Gram-positive and Gram-negative peritonitis revealed no significant changes over time. No case of vancomycin resistance was identified. There was a downward trend in peritonitis-related hospitalization over time to 0.11 ep/p-y (p ≤ 0.001). Trend analysis showed a favorable, but changing evolution, highlighting the importance of accurate longitudinal PD center registry data and quality control.
Ana Rocha; Anabela Rodrigues; Laetitia Teixeira; Maria João Carvalho; Denisa Mendonça; António Cabrita
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-10
Journal Detail:
Title:  Blood purification     Volume:  33     ISSN:  1421-9735     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402040     Medline TA:  Blood Purif     Country:  -    
Other Details:
Languages:  ENG     Pagination:  284-291     Citation Subset:  -    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Nephrology Department, CHP-Hospital Santo Antonio, Porto, Portugal.
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