Document Detail


Temperature effect on the transport dynamics of a small molecule through a liposome bilayer.
MedLine Citation:
PMID:  17665090     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An ion having hydrophobic parts can directly transport through the liposome bilayer without an ion channel and its transport mechanism can be explained by the free-volume theory. This was confirmed by investigating the temperature effect on the transport dynamics of organic cations through anionic liposome bilayers made of unsaturated and saturated lipids by using optical second-harmonic generation (SHG) technique. This study provides useful information to design practical temperature-controlled drug delivery systems.
Authors:
J H Kim; M W Kim
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-07-31
Journal Detail:
Title:  The European physical journal. E, Soft matter     Volume:  23     ISSN:  1292-8941     ISO Abbreviation:  Eur Phys J E Soft Matter     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-08-16     Completed Date:  2007-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101126530     Medline TA:  Eur Phys J E Soft Matter     Country:  France    
Other Details:
Languages:  eng     Pagination:  313-7     Citation Subset:  IM    
Affiliation:
Department of Physics, Korea Advanced Institute of Science and Technology, 305-701 Daejeon, Korea.
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MeSH Terms
Descriptor/Qualifier:
Biopolymers / chemistry*
Computer Simulation
Diffusion
Lipid Bilayers / chemistry*
Liposomes / chemistry*
Models, Chemical*
Temperature
Chemical
Reg. No./Substance:
0/Biopolymers; 0/Lipid Bilayers; 0/Liposomes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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