Document Detail


Temperature-dependent growth and regression of epidermal tumors in the european eel (Anguilla anguilla L.).
MedLine Citation:
PMID:  280183     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The population of eels in the Elbe estuary showed a high rate of affliction with epidermal papillomas. Distinct seasonal fluctuations were observed in the frequency of occurrence and tumor size. In spring and autumn, the frequency was low, and the tumors were relatively small. In summer, the tumors reached a maximum in both frequency and size. A distinct influence of water temperature on tumor growth was demonstrated experimentally. Summer temperatures of 15--22 degrees C caused very rapid growth. In the field and in the laboratory, the tumors exhibited a fourfold increase in average volume within 3 months. These fast-growing neoplasms had certain relatively uniform histologic features. The tumor cells were separated by wide intercellular spaces. The basal layer was composed of tall columnar cells, while the surface layer was composed of slightly flattened cells. Winter water temperatures (5--10 degrees C) inhibited tumor growth and even caused tumor regression. In 3 months, the papillomas shrank to half of their initial size. Histologic and ultrastructural examinations revealed signs of tissue degeneration: necrobiotic processes in the epidermal region, cellular and nuclear polymorphisms, dissolution of membranes, loss of cell integrity, and loosening and reduction in size of the basal cell layer.
Authors:
G Peters; N Peters
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  298     ISSN:  0077-8923     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  1978 Sep 
Date Detail:
Created Date:  1978-12-29     Completed Date:  1978-12-29     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  245-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anguilla*
Animals
Fish Diseases / etiology*,  pathology
Papilloma / etiology,  pathology,  veterinary*
Recurrence
Remission, Spontaneous
Seasons
Skin Diseases / etiology,  veterinary*
Skin Neoplasms / pathology
Temperature

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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