| Temperature dependence of rat circadian pacemaker. | |
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MedLine Citation:
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PMID: 7246797 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blind female rats were maintained in running-wheel cages in a 12-h light-dark cycle. Hypothermia was induced by ether anesthesia, wetting of the fur by ethanol, and covering with ice. Rats were put in restraining cages and colonic temperatures were maintained between 20 and 32 degrees C for 3-16 h by cooling with ice and water. On recovery from hypothermia, the rats were replaced in their home wheels. Examination of the activity records showed significant phase delays associated with temperatures lower than 28 degrees C. At 20 degrees C, the phase delays indicated that the clock was running at about 64% normal speed giving a mean Q10 of 1.33, which is quite a bit higher than previously reported. It is speculated that, because the rat maintains its body temperature within narrow limits after the neonatal stage, it has lost the precise temperature compensation for the period of its biological clock that has been so well documented in other organisms. |
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Authors:
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F P Gibbs |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of physiology Volume: 241 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1981 Jul |
Date Detail:
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Created Date: 1981-08-27 Completed Date: 1981-08-27 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R17-20 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blindness Body Temperature* Body Temperature Regulation* Circadian Rhythm* Cold Temperature Female Hypothermia / physiopathology Rats Species Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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