| Temperature and Heart Rate Responses to Exercise following Mild Traumatic Brain Injury. | |
| | |
MedLine Citation:
|
PMID: 23009619 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
We have previously reported that mild fluid percussion injury (FPI) is associated with a heightening of the hypothalamic-pituitary-adrenal axis response during the first postinjury weeks. This is the same time period when rehabilitative exercise has been strongly suggested to be ineffective. Here we explored if cardiac and temperature autonomic function may also be compromised during this early postinjury period. Following a FPI or sham injury, rats were exercised with forced (fRW) or voluntary (vRW) running wheels on post-injury days 0-4 and 7-11. Results indicated that overall activity levels were decreased and circadian rhythm was affected after FPI. Autonomic disruptions became evident when exercise was introduced and these disruptions were dependent on the characteristics of exercise. Elevations in heart rate (HR) and core body temperature (CBT) were observed as a response to vRW and fRW. FPI animals had more pronounced increases in HR as a result of vRW. Likewise, increases in HR were observed with fRW in all animals. A strong stress response has recently been associated with fRW exercise. FPI rats exposed to fRW were more responsive to experimental manipulations and had higher a CBT after the FRW session. The results suggest that subacute exercise, particularly if linked to a strong stress response, may be counterproductive. Here we show that cardiac and temperature autonomic function are compromised during the subacute period following a mild TBI. |
| | |
Authors:
|
Grace Sophia Griesbach; Delia L Tio; Shyama Nair; David Hovda |
Related Documents
:
|
748429 - Training and oxygen conductance in the elderly. ii. the cardiovascular system. 6624939 - Thermodilution method overestimates low cardiac output in humans. 6697639 - Reduction of digoxin effect during the digoxin-quinidine interaction. 6489759 - Dyspnea in the elderly: old age or disease? 7107469 - Heart rate adaptation to exercise training in cardiac-denervated dogs. 6814629 - Abnormal cardiac enzyme responses after strenuous exercise: alternative diagnostic aids. 7243889 - Electromyographic activity recorded from an unexercised muscle during maximal isometric... 12027329 - Instructors' and classroom characteristics associated with exercise enjoyment by females. 3962859 - Usefulness of early exercise testing after non-q-wave myocardial infarction in predicti... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-9-25 |
Journal Detail:
|
Title: Journal of neurotrauma Volume: - ISSN: 1557-9042 ISO Abbreviation: J. Neurotrauma Publication Date: 2012 Sep |
Date Detail:
|
Created Date: 2012-9-26 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8811626 Medline TA: J Neurotrauma Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
UCLA School of Medicine, Neurosurgery, Los Angeles, California, United States; ggriesbach@mednet.ucla.edu. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mass Spectrometry Imaging on Porous Silicon: Investigating the Distribution of Bioactives in the Mar...
Next Document: Illustration of extensive extracellular matrix at the epithelial-mesenchymal interface within the re...