Document Detail


Temozolomide combined with radiotherapy in the treatment of recurrent cranial meningioma previously treated with multiple surgical resections and two sessions of radiosurgery: a case report and literature review.
MedLine Citation:
PMID:  22825521     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Meningioma is a common primary brain tumor in adults. The treatment approach depends on its grade, size and symptoms. The case reported here was a repeatedly recurring transitional meningioma, previously treated with several surgical procedures and two sessions of cranial radiosurgery. At the time of last relapse, temozolomide was administered alone and combined with external beam radiation therapy. At the last follow-up after 38 months, the disease was stable. In conclusion, in this case of plurirecurrent meningioma, treatment with temozolomide alone and in combination with radiotherapy was feasible and associated with limited morbidity, providing clinical benefit and long local disease control. We discuss the case comparing our approach with other experiences reported in the literature.
Authors:
Marta Scorsetti; Filippo Alongi; Elena Clerici; Pierina Navarria; Matteo Simonelli; Elisa Rognone; Armando Santoro
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tumori     Volume:  98     ISSN:  2038-2529     ISO Abbreviation:  Tumori     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-07-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0111356     Medline TA:  Tumori     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  67e-71e     Citation Subset:  IM    
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