Document Detail

Telocytes, a distinct type of cell among the stromal cells present in the lamina propria of jejunum.
MedLine Citation:
PMID:  22763879     Owner:  NLM     Status:  In-Data-Review    
Conventionally, cells described in the stroma of the intestinal wall are fibroblasts/fibrocytes, mast cells, plasma cells, eosinophils, macrophages and, interstitial cells of Cajal (ICCs), the latter being considered as the pacemakers of gastrointestinal rhythmicity. Recently, a new type of stromal cell called telocyte (TCs) was found in various cavitary and non-cavitary organs ( We show here direct electron microscopical evidence for the presence of TCs in the lamina propria of rat jejunum just beneath the epithelial layer of the mucosal crypts and in between the smooth muscle cells (SMCs) of muscularis mucosae. TCs are characterized by: several very long (tens to hundreds of µm) prolongations called telopodes (Tps). Tps (with caliber below the resolving power of light microscopy) display podomeres (thin segments ≤0.2 µm) and podoms (dilations accommodating caveolae, mitochondria, and endoplasmic reticulum). Tps present dichotomous branching and form a three dimensional network close to immune cells, SMCs or nerve bundles. TCs could play a role in intercellular signaling and control of local tissue homeostasis.
D Cretoiu; S M Cretoiu; A A Simionescu; L M Popescu
Related Documents :
3494249 - Cdna cloning and sequence of mal, a hydrophobic protein associated with human t-cell di...
19766189 - Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopami...
16665359 - A plasmamembrane redox system and proton transport in isolated mesophyll cells.
16657669 - Spectral, physical, and electron transport activities in the photosynthetic apparatus o...
16103369 - Microoxen: microorganisms to move microscale loads.
9231419 - On the unidirectionality of arginine uptake in the yeast saccharomyces cerevisiae.
1203959 - Rate of protein synthesis in rat salivary gland cells after pilocarpine or feeding. i. ...
6902969 - The role of plasma transferrin in iron absorption in the rat.
366609 - Methionine analogs and cell division regulation in the yeast saccharomyces cerevisiae.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Histology and histopathology     Volume:  27     ISSN:  1699-5848     ISO Abbreviation:  Histol. Histopathol.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8609357     Medline TA:  Histol Histopathol     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  1067-78     Citation Subset:  IM    
Department of Cellular and Molecular Medicine, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Regular consumption of a silicic acid-rich water prevents aluminium-induced alterations of nitrergic...
Next Document:  Effects of Helicobacter pylori on biological characteristics of gastric epithelial cells.