| Telephone interview for cognitive status (TICS) screening for clinical trials of physical activity and cognitive training: the seniors health and activity research program pilot (SHARP-P) study. | |
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MedLine Citation:
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PMID: 21229597 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To examine the performance of the Telephone Interview for Cognitive Status (TICS) for identifying participants appropriate for trials of physical activity and cognitive training interventions. METHODS: Volunteers (N=343), ages 70-85 years, who were being recruited for a pilot clinical trial on approaches to prevent cognitive decline, were administered TICS and required to score ≥ 31 prior to an invitation to attend clinic-based assessments. The frequencies of contraindications for physical activity and cognitive training interventions were tallied for individuals grouped by TICS scores. Relationships between TICS scores and other measures of cognitive function were described by scatterplots and correlation coefficients. RESULTS: Eligibility criteria to identify candidates who were appropriate candidates for the trial interventions excluded 51.7% of the volunteers with TICS<31. TICS scores above this range were not strongly related to cognition or attendance at screening visits, however overall enrollment yields were approximately half for participants with TICS=31 versus TICS=41, and increased in a graded fashion throughout the range of scores. CONCLUSIONS: Use of TICS to define eligibility criteria in trials of physical activity and cognitive training interventions may not be worthwhile in that many individuals with low scores would already be eliminated by intervention-specific criteria and the relationship of TICS with clinic-based tests of cognitive function among appropriate candidates for these interventions may be weak. TICS may be most useful in these trials to identify candidates for oversampling in order to obtain a balanced cohort of participants at risk for cognitive decline. |
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Authors:
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Mark A Espeland; Stephen R Rapp; Jeff A Katula; Lee Ann Andrews; Deborah Felton; Sarah A Gaussoin; Dale Dagenbach; Claudine Legault; Janine M Jennings; Kaycee M Sink; |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: International journal of geriatric psychiatry Volume: 26 ISSN: 1099-1166 ISO Abbreviation: Int J Geriatr Psychiatry Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710629 Medline TA: Int J Geriatr Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 135-43 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 John Wiley & Sons, Ltd. |
Affiliation:
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Division of Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, USA. mespelan@wfubmc.edu |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00688155 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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1R01AG029285-01A1/AG/NIA NIH HHS; M01-RR07122/RR/NCRR NIH HHS |
| Investigator | |
Investigator/Affiliation:
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Robert Amoroso / ; Lee Ann Andrews / ; Jerry Barnes / ; Mary Barr / ; Dale Dagenbach / ; Patricia Davis / ; Meredith Dobrosielski / ; Robin Dove / ; Mark A Espeland / ; Deborah Felton / ; Sarah A Jaramillo / ; Janine M Jennings / ; Jeff A Katula / ; Mark D King / ; Claudine Legault / ; Abbie Prescott / ; Stephen Rapp / ; Jack Rejeski / ; Wes Roberson / ; Kaycee M Sink / ; Shannon Sharp / ; Sally A Shumaker / ; Terri Windham / ; Deborah E Barnes / ; Victor W Henderson / ; Abby C King / ; Marcia L Stefanick / |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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