| TELANG LIVER AND VITAMIN A TOXICITY. | |
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MedLine Citation:
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PMID: 17743365 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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(1) About 20 per cent. of fresh telang livers were toxic to weanling rats receiving the calcium supplemented livers as their sole dietary. (2) The symptoms observed in rats were growth failure and multiple spontaneous fractures of the bones of the extremities. (3) The toxicity of certain telang livers was due to their abnormally high stores of vitamin A. When these livers, supplemented only with calcium carbonate, were fed to weanling rats, the daily intake of vitamin A was in excess of the toxic dosage of 15,000 I.U. per day. (4) Identical symptoms of toxicity were observed in weanling rats fed 20,000 I.U. of crystalline vitamin A per day in conjunction with a standard stock ration. |
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Authors:
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E J Herbst; P L Pavcek; C A Elvehjem |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 100 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1944 Oct |
Date Detail:
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Created Date: 2010-06-03 Completed Date: 2010-07-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: United States |
Other Details:
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Languages: eng Pagination: 338-9 Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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